Specific Gray Matter Volume Changes of the Brain in Unipolar and Bipolar Depression
نویسندگان
چکیده
منابع مشابه
Bipolar and unipolar depression.
Since Kraepelin grouped affective disorders under the title of 'manic-depressive insanity', there has been controversy over whether the bipolar and unipolar entities within this are distinct affective disorders or whether they are merely two ends of an affective continuum. In order to bring some clarity and goal-posts to this argument, we define the criteria that must be fulfilled by diseases i...
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Objective There is increasing evidence that BrainDerived Neurotrophic Factor may be involved in the pathophysiology of depression and the actions of antidepressants. At the same time, the differential diagnosis between unipolar and bipolar depression is often a challenge with important treatment implications. The aim of the present study was to analyze the relationship between BrainDerived Neur...
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BACKGROUND To identify changes in brain activation patterns in bipolar disorder (BD) and unipolar depression (UD) patients. METHODOLOGY/PRINCIPAL FINDINGS Resting-state fMRI scans of 16 healthy controls, 17 BD and 16 UD patients were obtained. T-test of normalized regional homogeneity (ReHo) was performed in a voxel-by-voxel manner. A combined threshold of á = 0.05, minimum cluster volume of ...
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OBJECTIVE Subcortical limbic structures have been proposed to be involved in the pathophysiology of adult and pediatric bipolar disorder (BD). We sought to study morphometric characteristics of these structures in pediatric subjects with familial BD compared with healthy controls. METHOD Twenty children and adolescents with BD I (mean age = 14.6 years, four females) and 20 healthy age, gender...
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AIMS AND METHOD To review the evidence for this use of pramipexole in the treatment of unipolar and bipolar depression, a literature search on Embase and Medline was conducted in December 2003. The search was updated in July 2004. The reference sections of retrieved papers were searched for further relevant references. RESULTS There are limited data on the clinical use of pramipexole in affecti...
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ژورنال
عنوان ژورنال: Frontiers in Human Neuroscience
سال: 2021
ISSN: 1662-5161
DOI: 10.3389/fnhum.2020.592419